سیتوگلوبین
Sign in to saveAlso known as histoglobin, CYGB, cytoglobin, HGb, stellate cell activation-associated protein
Cytoglobin is the protein product of CYGB, a human and mammalian gene.
Protein · UniProt
Cytoglobin
- Gene
- CYGB
- Organism
- Homo sapiens (Human)
- Length
- 190 aa
- Molecular mass
- 21,405 Da
- Evidence
- 1: Evidence at protein level
Probable multifunctional globin with a hexacoordinated heme iron required for the catalysis of various reactions depending on redox condition of the cell as well as oxygen availability (PubMed:11893755, PubMed:12359339, PubMed:15165856, PubMed:19147491, PubMed:20511233, PubMed:28393874, PubMed:28671819, PubMed:29128400, PubMed:33576020, PubMed:34930834). Has a nitric oxide dioxygenase (NOD) activity and is most probably involved in cell-mediated and oxygen-dependent nitric oxide consumption (PubMed:19147491, PubMed:20511233, PubMed:28393874, PubMed:28671819). By scavenging this second messe…
Swiss-Prot (reviewed) · via UniProt
Research
446 papers- Insights into the function of cytoglobin.Biochemical Society transactions · 2023
- Emerging perspectives on cytoglobin, beyond NO dioxygenase and peroxidase.Redox biology · 2020
- Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis.Clinical and molecular hepatology · 2020
- Cytoglobin scavenges intracellular hydrogen peroxide and regulates redox signals in the vasculature.Redox biology · 2025
- Cytoglobin has potent superoxide dismutase function.Proceedings of the National Academy of Sciences of the United States of America · 2021
via PubMed
Wikidata facts
- Instance of
- protein
Show 3 more facts
- molecular function
- protein binding
- found in taxon
- Homo sapiens
- exact match
- purl.uniprot.org/uniprot/Q8WWM9
Sources (3)
via Wikidata · CC0