Hemoglobin subunit beta
Sign in to saveAlso known as hemoglobin beta subunit, beta globin chain, hemoglobin, beta, Beta-globin, Hemoglobin beta chain, HBB
mammalian protein found in Homo sapiens
Protein · UniProt
Hemoglobin subunit beta
- Gene
- HBB
- Organism
- Homo sapiens (Human)
- Length
- 147 aa
- Molecular mass
- 15,998 Da
- Evidence
- 1: Evidence at protein level
Involved in oxygen transport from the lung to the various peripheral tissues
3D-structureAcetylationCongenital dyserythropoietic anemiaDirect protein sequencingDisease variantGlycationGlycoproteinHeme
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Swiss-Prot (reviewed) · via UniProt
Clinical Trials
8 registered- PHASE1/PHASE2RECRUITINGAn Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-ThalassemiaLantu Biopharma · NCT06308159
- COMPLETEDDemographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia IntermediaHaEmek Medical Center, Israel · NCT01443312
- PHASE1/PHASE2COMPLETEDStem Cell Gene Therapy for Sickle Cell DiseaseDonald B. Kohn, M.D. · NCT02247843
- PHASE1/PHASE2RECRUITINGEfficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA.Assistance Publique - Hôpitaux de Paris · NCT07432867
- PHASE1/PHASE2UNKNOWNGene Therapy for Transfusion Dependent Beta-thalassemiaIRCCS San Raffaele · NCT02453477
- PHASE1RECRUITINGSingle-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell DiseaseFulcrum Therapeutics · NCT07431398