darolutamide
Sign in to saveAlso known as ODM-201, BAY-1841788
Darolutamide, sold under the brand name Nubeqa, is an antiandrogen medication which is used in the treatment of non-metastatic castration-resistant prostate cancer in men. It is specifically approved to treat non-metastatic castration-resistant prostate cancer (nmCRPC) in conjunction with surgical or medical castration. The medication is taken by mouth twice per day with food.
Key facts
- Drug.Verifiedfields
- verified
- Drug.verifiedrevid
- 459978482
- Drug.image
- ODM-201.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- Darolutamide molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Nubeqa
- Drug.MedlinePlus
- a619045
- Drug.licence_EU
- yes
- Drug.DailyMedID
- Darolutamide
- Drug.pregnancy_AU
- X
- Drug.routes_of_administration
- By mouth
- Drug.class
- Nonsteroidal antiandrogen
- Drug.ATC_prefix
- L02
- Drug.ATC_suffix
- BB06
- Drug.legal_AU
- S4
via Wikipedia infobox
~15 min read
Encyclopedic overview
23 sectionsContents
- Medical uses
- Available forms
- Contraindications
- Side effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Excretion
- Variability
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Research
- References
- External links
Darolutamide, sold under the brand name Nubeqa, is an antiandrogen medication which is used in the treatment of non-metastatic castration-resistant prostate cancer in men. It is specifically approved to treat non-metastatic castration-resistant prostate cancer (nmCRPC) in conjunction with surgical or medical castration. The medication is taken by mouth twice per day with food.
Side effects of darolutamide added to castration may include fatigue, asthenia, pain in the arms and legs, and rash. Darolutamide is a nonsteroidal antiandrogen (NSAA), and acts as a selective antagonist of the androgen receptor (AR). It has been referred to as a second- or third-generation NSAA.
Excerpted from Wikipedia’s “darolutamide” article, available under the CC BY-SA 4.0 licence.