benzydamine
Sign in to savethumb|Benzydamine medicinal mouthwash as sold in Argentina. Benzydamine (also known as Tantum Verde and branded in some countries as Maxtra Gargle, Difflam and Septabene), available as the hydrochloride salt, is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions of the mouth and throat. It falls under class of chemicals known as indazoles.
Key facts
- Drug.verifiedrevid
- 414278352
- Drug.IUPAC_name
- 3-(1-benzyl-1H-indazol-3-yloxy)-N,N-dimethylpropan-1-amine
- Drug.image
- Benzydamine-2D-skeletal.png
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Maxtra Gargle, Difflam, Tantum verde
- Drug.pregnancy_AU
- B2
- Drug.routes_of_administration
- Oral, topical
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- /Schedule 2
- Drug.legal_BR
- C1
- Drug.legal_UK
- P and POM
- Drug.legal_EU
- OTC
- Drug.protein_bound
- <20%
- Drug.elimination_half life
- 13 hours
- Drug.excretion
- Kidney
- Drug.CAS_number
- 642-72-8
- Drug.ATC_prefix
- A01
- Drug.ATC_suffix
- AD02
via Wikipedia infobox
Research
693 papers- Benzydamine hydrochloride: an overview on a well-established drug with news in mechanisms of action.F1000Research · 2024
- Benzydamine-An Affordable Over-the-Counter Drug with Psychoactive Properties-From Chemical Structure to Possible Pharmacological Properties.Pharmaceuticals (Basel, Switzerland) · 2023
- The Benzydamine Experience: A Systematic Review of Benzydamine Abuse.Current neuropharmacology · 2021
- PMID 308307322018
- PMID 308557692018
via PubMed
Article
12 sectionsContents
- History
- Uses
- Medical
- Recreational
- Contraindications
- Side effects
- Pharmacology
- Pharmacokinetic
- Synthesis
- Research
- References
- External links
thumb|Benzydamine medicinal mouthwash as sold in Argentina. Benzydamine (also known as Tantum Verde and branded in some countries as Maxtra Gargle, Difflam and Septabene), available as the hydrochloride salt, is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions of the mouth and throat. It falls under class of chemicals known as indazoles.
==History== It was synthesized in Italy in 1964 and marketed in 1966.