درروبون

Derrubone is a prenylated isoflavone, a type of flavonoid. It was originally isolated from the Indian tree Derris robusta. Recent research indicates that it acts as an inhibitor of Hsp90 to its function as a chaperone protein.

Chemical data

Formula: C21H18O6
Molecular weight: 366.4 g/mol
IUPAC name: 3-(1,3-benzodioxol-5-yl)-5,7-dihydroxy-6-(3-methylbut-2-enyl)chromen-4-one
SMILES: CC(=CCC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC4=C(C=C3)OCO4)O)C
InChIKey: FTBGFGQPUMCUSC-UHFFFAOYSA-N
XLogP: 4.8
Polar surface area: 85.2 Å²
H-bond donors: 2
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: isoflavonoid
Mass: 366.11

Show 2 more facts

chemical formula: C₂₁H₁₈O₆
canonical SMILES: CC(=CCC1=C(C=C2C(=C1O)C(=O)C(=CO2)C3=CC4=C(C=C3)OCO4)O)C

Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0