dideoxynucleotide
Sign in to savethumb|Molecular structure of 2',3'-dideoxyadenosine triphosphate (ddATP)
Article
5 sectionsContents
- Role in the Sanger method
- DNA Sequencing
- Production
- References
- External links
thumb|Molecular structure of 2',3'-dideoxyadenosine triphosphate (ddATP)
Dideoxynucleotides are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing. They are also known as 2',3' because both the 2' and 3' positions on the ribose lack hydroxyl groups, and are abbreviated as ddNTPs (ddGTP, ddATP, ddTTP and ddCTP).