Structure via PubChem · Public domain (PubChem)
دیهیدروتستوسترون
Sign in to saveAlso known as DHT, 5alpha-Dihydrotestosterone, 17beta-Hydroxy-5alpha-androstan-3-one, Androstanolone, Stanolone, 17β-hydroxy-5α-androstan-3-one, Dihydrotestosterone, 17beta-Hydroxyandrostan-3-one
هورمون استروئیدی جنسی
Chemical data
- Formula
- C19H30O2
- Molecular weight
- 290.4 g/mol
- IUPAC name
- (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C
- InChIKey
- NVKAWKQGWWIWPM-ABEVXSGRSA-N
- XLogP
- 3.7
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- hypogonadism
via ChEMBL · EBI
Research
15,537 papers- Dihydrotestosterone metabolism.Clinics in endocrinology and metabolism · 1986
- [5alpha-dihydrotestosterone (DHT)].Nihon rinsho. Japanese journal of clinical medicine · 2005
- Testosterone or dihydrotestosterone: what should be evaluated in hirsutism?Irish journal of medical science · 2023
- Is Dihydrotestosterone a Classic Hormone?Endocrine reviews · 2017
- Update on the use of trilostane in dogs.The Canadian veterinary journal = La revue veterinaire canadienne · 2018
via PubMed
Wikidata facts
Show 6 more facts
- chemical formula
- C₁₉H₃₀O₂
- isomeric SMILES
- C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C
- subject has role
- primary metabolite
- Commons category
- Dihydrotestosterone
- physically interacts with
- androgen receptor
- canonical SMILES
- O=C1CCC2(C)C(C1)CCC3C4CCC(O)C4(C)CCC32
via Wikidata · CC0