SRD5A1

Also known as S5AR 1, steroid 5 alpha-reductase 1

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. It is one of three forms of steroid 5α-reductase.

Gene data

SRD5A1

Name: steroid 5 alpha-reductase 1
Type: protein-coding
Aliases: S5AR 1

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008].

via MyGene.info

Gene · Ensembl

steroid 5 alpha-reductase 1

Symbol: SRD5A1
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:6,633,290-6,676,539
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 37426
exact match: identifiers.org/ncbigene/6715
cytogenetic location: 5p15.31
genomic start: 6633427
genomic end: 6669675

Sources (3)

via Wikidata · CC0

~3 min read

Article

7 sections

Contents

Function
Regulation
Clinical significance
Expression
See also
References
Further reading

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. It is one of three forms of steroid 5α-reductase.

Steroid 5α-reductase (EC 1.3.99.5) catalyzes, among other reactions, the conversion of testosterone into the more potent androgen, 5α-dihydrotestosterone (DHT). The SRD5A1, SRD5A2, and SRD5A3 genes in humans all encode 5α-reductase isozymes.