SRD5A1
Sign in to saveAlso known as S5AR 1, steroid 5 alpha-reductase 1
3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. It is one of three forms of steroid 5α-reductase.
Gene data
SRD5A1- Name
- steroid 5 alpha-reductase 1
- Type
- protein-coding
- Position
- 6,633,290–6,676,539 (+)
- Aliases
- S5AR 1
- Ensembl
- ENSG00000145545
- RefSeq RNA
- NM_001047.4, NM_001324322.2, NM_001324323.2, NR_136739.2
- RefSeq protein
- NP_001038.1, NP_001311251.1, NP_001311252.1
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
steroid 5 alpha-reductase 1
- Symbol
- SRD5A1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:6,633,290-6,676,539
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 37426
- exact match
- identifiers.org/ncbigene/6715
- cytogenetic location
- 5p15.31
- genomic start
- 6633427
- chromosome
- human chromosome 5
- genomic end
- 6669675
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Function
- Regulation
- Clinical significance
- Expression
- See also
- References
- Further reading
3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. It is one of three forms of steroid 5α-reductase.
Steroid 5α-reductase (EC 1.3.99.5) catalyzes, among other reactions, the conversion of testosterone into the more potent androgen, 5α-dihydrotestosterone (DHT). The SRD5A1, SRD5A2, and SRD5A3 genes in humans all encode 5α-reductase isozymes.
Excerpted from Wikipedia’s “SRD5A1” article, available under the CC BY-SA 4.0 licence.