DRD5
Sign in to saveAlso known as DBDR, DRD1B, DRD1L2, dopamine receptor D5
protein-coding gene in the species Homo sapiens
Gene data
DRD5- Name
- dopamine receptor D5
- Type
- protein-coding
- Position
- 9,781,387–9,784,012 (+)
- Aliases
- DBDR, DRD1B, DRD1L2
- Ensembl
- ENSG00000169676
- RefSeq RNA
- NM_000798.5
- RefSeq protein
- NP_000789.1
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
synaptic transmission, dopaminergicintracellular calcium ion homeostasisG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating dopamine receptor signaling pathwayG protein-coupled dopamine receptor signaling pathwaychemical synaptic transmission
Molecular function
dopamine neurotransmitter receptor activity, coupled via Gsdopamine neurotransmitter receptor activity, coupled via Gsdopamine neurotransmitter receptor activity, coupled via Gsdopamine neurotransmitter receptor activity, coupled via GsG protein-coupled receptor activityG protein-coupled receptor activitydopamine neurotransmitter receptor activitydopamine neurotransmitter receptor activity
Pathways
Calcium signaling pathway - Homo sapiens (human)cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Dopaminergic synapse - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Amine ligand-binding receptorsGPCR downstream signallingDopamine receptors
via MyGene.info
Gene · Ensembl
dopamine receptor D5
- Symbol
- DRD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:9,781,387-9,784,012
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 20216
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1816
- genomic end
- 9785632
- genomic start
- 9781634
- chromosome
- human chromosome 4
- cytogenetic location
- 4p16.1
- genetic association
- blepharospasm
Sources (3)
via Wikidata · CC0
Available in 9 languages
via Wikidata sitelinks · CC0