Structure via PubChem · Public domain (PubChem)
اداراوون
Sign in to saveAlso known as developer Z, C.I. developer 1, norphenazone, 3-methyl-1-phenyl-2-pyrazolin-5-one, 3-methyl-1-phenyl-5-pyrazolone, 3-methyl-1-phenylpyrazol-5-one, methylphenylpyrazolone, phenylmethylpyrazolone
Edaravone, sold under the brand name Radicava among others, is a medication used to treat stroke and amyotrophic lateral sclerosis (ALS). It is given by intravenous infusion and by mouth.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443718859
- Drug.image
- Edaravone Structural Formula V1.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 160
- Drug.image2
- Edaravone ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Radicava, others
- Drug.MedlinePlus
- a617027
- Drug.DailyMedID
- Edaravone
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- Intravenous, by mouth
- Drug.ATC_prefix
- N07
- Drug.ATC_suffix
- XX14
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_status
- Rx-only
via Wikipedia infobox
Chemical data
- Formula
- C10H10N2O
- Molecular weight
- 174.2 g/mol
- IUPAC name
- 5-methyl-2-phenyl-4H-pyrazol-3-one
- SMILES
- CC1=NN(C(=O)C1)C2=CC=CC=C2
- InChIKey
- QELUYTUMUWHWMC-UHFFFAOYSA-N
- XLogP
- 1.3
- Polar surface area
- 32.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2017
- Admin. routes
- oral, parenteral
- Indications
- stroke, liver disease, kidney disease, brain injury
via ChEMBL · EBI
Research
2,015 papers- Edaravone Dexborneol Versus Edaravone Alone for the Treatment of Acute Ischemic Stroke: A Phase III, Randomized, Double-Blind, Comparative Trial.Stroke · 2021
- Edaravone for patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis.Acta neurologica Belgica · 2024
- Edaravone May Prevent Ferroptosis in ALS.Current drug targets · 2020
- Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs.Medicinal research reviews · 2019
- Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis.JAMA neurology · 2022
via PubMed
Wikidata facts
- Subclass of
- alkaloid
- Mass
- 174.079
- Has use
- medication
Show 8 more facts
- Commons category
- Edaravone
- chemical formula
- C₁₀H₁₀N₂O
- canonical SMILES
- CC1=NN(C(=O)C1)C2=CC=CC=C2
- found in taxon
- Homo sapiens
- NCI Thesaurus ID
- C74323
- subject has role
- nootropic
- melting point
- 129
- medical condition treated
- ALS
Sources (7)
via Wikidata · CC0