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uric acid
Sign in to saveAlso known as urate, 2,6,8-Trihydroxypurine, 7,9-dihydro-1H-purine-2,6,8(3H)-trione
end product of nucleic acid degradation
OverviewAI-generated
Uric acid is a chemical compound with the formula C₅H₄N₄O₃. Its IUPAC name is 7,9-dihydro-3H-purine-2,6,8-trione. The substance has a mass of 168.028 and a density of 1.89. It possesses a charge of 0, an xlogp of -1.9, and a tpsa of 99.3. The molecule contains four hydrogen bond donors and three hydrogen bond acceptors.
The canonical SMILES representation for uric acid is C12=C(NC(=O)N1)NC(=O)NC2=O. A PubChem entry lists its weight as 168.11. The compound is associated with a Commons category titled "Uric acid".
Literature on uric acid includes 53676 entries in PubMed. The subject is referenced by 480 other encyclopedia articles.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C5H4N4O3
- Molecular weight
- 168.11 g/mol
- IUPAC name
- 7,9-dihydro-3H-purine-2,6,8-trione
- SMILES
- C12=C(NC(=O)N1)NC(=O)NC2=O
- InChIKey
- LEHOTFFKMJEONL-UHFFFAOYSA-N
- XLogP
- -1.9
- Polar surface area
- 99.3 Ų
- H-bond donors
- 4
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
53,676 papers- Uric acid nephrolithiasis: An update.ReviewUrologia · 2018Cicerello EDOI: 10.1177/0391560318766823
- Uric Acid as a Marker of Kidney Disease: Review of the Current Literature.ReviewDisease markers · 2015Giordano C, Karasik O, King-Morris K et al.DOI: 10.1155/2015/382918
- Uric acid calculi.The Journal of urology · 1957ALLYN REDOI: 10.1016/S0022-5347(17)66440-1
- Drugs and uric acid.ReviewAnnual review of pharmacology · 1969Rundles RW, Wyngaarden JBDOI: 10.1146/annurev.pa.09.040169.002021
- Ethanol metabolism and uric acid.ReviewMetabolism: clinical and experimental · 1972Newcombe DSDOI: 10.1016/0026-0495(72)90115-1
- Mechanistic Insights of Soluble Uric Acid-related Kidney Disease.Current medicinal chemistry · 2020Pan J, Shi M, Ma L et al.DOI: 10.2174/0929867326666181211094421
- Role of uric acid in Alzheimer's disease.ReviewJournal of Alzheimer's disease : JAD · 2010Spitsin S, Koprowski HDOI: 10.3233/JAD-2010-1336
- Acute uric acid nephropathy.Archives of internal medicine · 1977Robinson RR, Yarger WE
via PubMed
~15 min read
Encyclopedic overview
Names
Preferred IUPAC name 7,9-Dihydro-1H-purine-2,6,8(3H)-trione
Excerpted from Wikipedia’s “uric acid” article, available under the CC BY-SA 4.0 licence.
Gallery (5)
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