pyrazolone
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Pyrazolone is 5-membered heterocycle containing two adjacent nitrogen atoms. It can be viewed as a derivative of pyrazole possessing an additional carbonyl (C=O) group. Compounds containing this functional group are useful commercially in analgesics and dyes.
Research
19,532 papers- Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect.European journal of medicinal chemistry · 2020
- Pyrazolone derivatives.Drugs · 1986
- [Pyrazolone allergy].Allergologia et immunopathologia · 1994
- Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors.European journal of medicinal chemistry · 2023
- Pyrazolone-Based Zn(II) Complexes Display Antitumor Effects in Mutant p53-Carrying Cancer Cells.Journal of medicinal chemistry · 2024
via PubMed
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Encyclopedic overview
7 sectionsContents
- Structure and synthesis
- Applications
- Pharmaceuticals
- Dyes
- Ligands
- References
- External links
Pyrazolone is 5-membered heterocycle containing two adjacent nitrogen atoms. It can be viewed as a derivative of pyrazole possessing an additional carbonyl (C=O) group. Compounds containing this functional group are useful commercially in analgesics and dyes.
==Structure and synthesis== Pyrazolone can exist in two isomers: 3-pyrazolone and 4-pyrazolone.
Excerpted from Wikipedia’s “pyrazolone” article, available under the CC BY-SA 4.0 licence.