EDC3
Sign in to saveAlso known as LSM16, YJDC, YJEFN2, MRT50, enhancer of mRNA decapping 3, hYjeF_N2-15q23
Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene.
Gene data
EDC3- Name
- enhancer of mRNA decapping 3
- Type
- protein-coding
- Aliases
- LSM16, MRT50, YJDC, YJEFN2, hYjeF_N2-15q23
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017].
via MyGene.info
Wikidata facts
- Image
- Protein EDC3 PDB 2VC8.png
Show 5 more facts
- HomoloGene ID
- 11827
- exact match
- identifiers.org/ncbigene/80153
- genomic end
- 74988633
- genomic start
- 74922899
- cytogenetic location
- 15q24.1
Sources (3)
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Article
2 sectionsContents
- References
- Further reading
Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene.
EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005).[supplied by OMIM]