DCP2
Sign in to saveAlso known as NUDT20, decapping mRNA 2
mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.
Gene data
DCP2- Name
- decapping mRNA 2
- Type
- protein-coding
- Position
- 112,976,702–113,028,477 (+)
- Aliases
- NUDT20
- Ensembl
- ENSG00000172795
- RefSeq RNA
- NM_001242377.2, NM_152624.6, NR_038352.2, XM_047416865.1, XM_047416866.1
- RefSeq protein
- NP_001229306.1, NP_689837.2, XP_047272821.1, XP_047272822.1, XP_047272823.1
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
decapping mRNA 2
- Symbol
- DCP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:112,976,702-113,028,477
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.
DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005).[supplied by OMIM]
Excerpted from Wikipedia’s “DCP2” article, available under the CC BY-SA 4.0 licence.