Endotelina 2
Sign in to saveAlso known as ET2, PPET2, ET-2, endothelin 2
protein-coding gene in the species Homo sapiens
Gene data
EDN2- Name
- endothelin 2
- Type
- protein-coding
- Position
- 41,478,774–41,500,502 (−)
- Aliases
- ET-2, ET2, PPET2
- Ensembl
- ENSG00000127129
- RefSeq RNA
- NM_001302269.2, NM_001956.5, NR_126098.2, XM_017000512.2, XM_054334817.1
- RefSeq protein
- NP_001289198.1, NP_001947.1, XP_016856001.2, XP_054190792.1, XP_054190793.1
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
endothelin 2
- Symbol
- EDN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:41,478,774-41,500,502
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1477
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1907
- genomic end
- 41484683
- genomic start
- 41944446
- chromosome
- human chromosome 1
- cytogenetic location
- 1p34.2
- expressed in
- trachea
Sources (4)
via Wikidata · CC0
Article · Italiano
Endotelina 2, anche nota come EDN2, è sia il nome di un gene umano sia il corrispondente peptide, e costituisce una delle tre isoforme delle endoteline umane.
Abstract from DBpedia / Wikipedia · CC BY-SA