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GeneQ18035963· pop 7· linked from 82 articles

Also known as H-PAST, HPAST1, PAST, PAST1, EH domain containing 1

EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family.

Gene data

EHD1
Name
EH domain containing 1
Type
protein-coding
Aliases
H-PAST, HPAST1, PAST, PAST1

This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013].

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Wikidata facts

Image
Protein EHD1 PDB 2JQ6.png
Show 5 more facts
HomoloGene ID
81678
genomic end
64655768
genomic start
64619114
cytogenetic location
11q13.1
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Article

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family.

== Function ==

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