EHD1
Sign in to saveAlso known as H-PAST, HPAST1, PAST, PAST1, EH domain containing 1
EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family.
Gene data
EHD1- Name
- EH domain containing 1
- Type
- protein-coding
- Position
- 64,851,642–64,888,372 (−)
- Aliases
- H-PAST, HPAST1, PAST, PAST1
- Ensembl
- ENSG00000110047
- RefSeq RNA
- NM_001282444.2, NM_001282445.2, NM_006795.4
- RefSeq protein
- NP_001269373.1, NP_001269374.1, NP_006786.2
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
EH domain containing 1
- Symbol
- EHD1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:64,851,642-64,888,372
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein EHD1 PDB 2JQ6.png
Show 7 more facts
- HomoloGene ID
- 81678
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10938
- genomic end
- 64655768
- genomic start
- 64619114
- chromosome
- human chromosome 11
- cytogenetic location
- 11q13.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family.
== Function ==
Excerpted from Wikipedia’s “EHD1” article, available under the CC BY-SA 4.0 licence.