endoribonuclease
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In biochemistry, an endoribonuclease is a class of enzyme which is a type of ribonuclease (an RNA cleaver), itself a type of endonuclease (a nucleotide cleaver). It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complexes of proteins with RNA such as RNase P and the RNA-induced silencing complex. Further examples include endoribonuclease XendoU found in frogs (Xenopus).
Research
30,181 papers- Substrate specificity of bacterial endoribonuclease toxins.BMB reports · 2020
- Endoribonuclease type II toxin-antitoxin systems: functional or selfish?Microbiology (Reading, England) · 2017
- The coronavirus nsp15 endoribonuclease: A puzzling protein and pertinent antiviral drug target.Antiviral research · 2024
- CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage.Nature communications · 2025
- Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L.Cell reports · 2024
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Wikidata facts
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- endonuclease
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In biochemistry, an endoribonuclease is a class of enzyme which is a type of ribonuclease (an RNA cleaver), itself a type of endonuclease (a nucleotide cleaver). It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complexes of proteins with RNA such as RNase P and the RNA-induced silencing complex. Further examples include endoribonuclease XendoU found in frogs (Xenopus).
==External links==
Excerpted from Wikipedia’s “endoribonuclease” article, available under the CC BY-SA 4.0 licence.