Structure via PubChem · Public domain (PubChem)
انفلوران
Sign in to saveAlso known as Forane®, Alyrane, Methylflurether, Ethrane, Efrane, 2-chloro-1,1,2-trifluoroethyl difluoromethyl ether, Enfluranum, Enflurane
Enflurane (2-chloro-1,1,2-trifluoroethyl difluoromethyl ether) is a halogenated ether. Developed by Ross Terrell in 1963, it was first used clinically in 1966. It was increasingly used for inhalational anesthesia during the 1970s and 1980s but is no longer in common use.
Key facts
- Drug.verifiedrevid
- 461093677
- Drug.IUPAC_name
- (RS)-2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
- Drug.image
- Enflurane.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Enflurane-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.legal_BR
- C1
- Drug.protein_bound
- 97%
- Drug.IUPHAR_ligand
- 7175
- Drug.CAS_number
- 13838-16-9
- Drug.ATC_prefix
- N01
- Drug.ATC_suffix
- AB04
- Drug.PubChem
- 3226
- Drug.DrugBank
- DB00228
- Drug.ChemSpiderID
- 3113
- Drug.UNII
- 91I69L5AY5
- Drug.KEGG
- D00543
- Drug.ChEBI
- 4792
via Wikipedia infobox
Chemical data
- Formula
- C3H2ClF5O
- Molecular weight
- 184.49 g/mol
- IUPAC name
- 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
- SMILES
- C(C(OC(F)F)(F)F)(F)Cl
- InChIKey
- JPGQOUSTVILISH-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 9.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1972
- Admin. routes
- topical
via ChEMBL · EBI
Research
3,639 papers- Enflurane.British journal of anaesthesia · 1979
- Enflurane.Anaesthesia and intensive care · 2007
- Enflurane hepatitis.Journal of clinical gastroenterology · 1982
- Enflurane today.Anaesthesia · 1980
- Enflurane as an anesthetic.Anaesthesia · 1977
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 183.971
- Has use
- medication
Show 11 more facts
- vapor pressure
- 175
- subject has role
- inhalational anaesthetic
- ceiling exposure limit
- 15.1
- Commons category
- Enflurane
- chemical formula
- C₃H₂ClF₅O
- NIOSH Pocket Guide ID
- 0253
- density
- 1.52
- boiling point
- 134
- medical condition treated
- status asthmaticus
- canonical SMILES
- C(C(OC(F)F)(F)F)(F)Cl
- global warming potential
- 705
Sources (6)
via Wikidata · CC0