EPHA4
Sign in to saveAlso known as 2900005C20Rik, AI385584, Cek8, Hek8, Sek, Sek1, Tyro1
protein-coding gene in the species Homo sapiens
Gene data
EPHA4- Name
- EPH receptor A4
- Type
- protein-coding
- Aliases
- EK8, HEK8, SEK, TYRO1
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015].
via MyGene.info
Gene · Ensembl
EPH receptor A4
- Symbol
- EPHA4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:221,418,027-221,574,202
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EPHA4 PDB 1b0x.png
Show 6 more facts
- HomoloGene ID
- 20933
- exact match
- identifiers.org/ncbigene/2043
- genomic end
- 222438922
- genomic start
- 222282747
- cytogenetic location
- 2q36.1
- Commons category
- EphA4 receptor
Sources (4)
via Wikidata · CC0