erythrityl tetranitrate

Chemical data

Formula

C4H6N4O12

Molecular weight

302.11 g/mol

IUPAC name

[(2R,3S)-1,3,4-trinitrooxybutan-2-yl] nitrate

SMILES

C([C@H]([C@H](CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]

InChIKey

SNFOERUNNSHUGP-ZXZARUISSA-N

XLogP

1.4

Polar surface area

220 Ų

H-bond donors

0

H-bond acceptors

12

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

Indications

cardiovascular disease

via ChEMBL · EBI

• Digital plethysmography for assessing erythrityl tetranitrate bioavailability.Clinical pharmacology and therapeutics · 1981
• Erythrityl tetranitrate: sustained effects on systolic time intervals. changes consistent with sustained preload reduction.The American journal of the medical sciences · 1979
• High-performance liquid chromatographic determination of the nitrate esters isosorbide dinitrate, pentaerythritol tetranitrate, and erythrityl tetranitrate in various tablet forms.Journal of pharmaceutical sciences · 1984
• Erythrityl tetranitrate compared with isosorbide dinitrate. Effects on systolic time intervals and nitrate modification of effects of food.Pharmacotherapy · 1983
• Erythrityl tetranitrate; drug efficacy study implementation; revocation of exemption; opportunity for a hearing--FDA. Notice.Federal register · 1998

via PubMed

Wikidata facts

Mass

301.998

Has use

medication

via Wikidata · CC0