エリスロポエチン
Also known as EPO, uniprot:P01588, epoetin
Erythropoietin (; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO (around 10 mU/mL) are constantly secreted in sufficient quantities to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10 000 mU/mL) include any anemia, and hypoxemia due to chronic lung disease.
AI overview
Erythropoietin (EPO) is a protein made mainly by the kidneys that tells your bone marrow to produce more red blood cells, especially when your body isn't getting enough oxygen. Your body uses it to maintain healthy red blood cell levels during normal conditions and ramps up production when conditions like anemia or lung disease reduce oxygen availability.
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- purl.uniprot.org/uniprot/P01588
Article · 日本語
エリスロポエチン（英語: erythropoietin; 略称: EPO）とは、赤血球の産生を促進する造血因子の一つ（ホルモンともサイトカインとも）。分子量は約34000、165個のアミノ酸から構成されている。血液中のエリスロポエチン濃度は、貧血、多血症などの鑑別診断に用いられる。腎性貧血の治療に主に使用されているが、ドーピングにも使用され問題となっている。
Abstract from DBpedia / Wikipedia · CC BY-SA