Structure via PubChem · Public domain (PubChem)
estazolam
Sign in to saveAlso known as D 40TA, 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine, Eurodin, ProSom, Estazolamum
Estazolam, sold under the brand name Prosom among others, is a tranquilizer medication of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Estazolam is an intermediate-acting oral benzodiazepine. It is used for short-term treatment of insomnia.
Key facts
- Drug.H
- 11
- Drug.Cl
- 1
- Drug.N
- 4
- Drug.image2
- Estazolam3d.png
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457289200
- Drug.image
- Estazolam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 170
- Drug.image_class2
- bg-transparent
- Drug.width2
- 170
- Drug.tradename
- Prosom, Esilgan, Eurodin, Nuctalon, others
- Drug.MedlinePlus
- a691003
- Drug.DailyMedID
- Estazolam
- Drug.pregnancy_US
- X
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.legal_DE
- Rx-only/Anlage III
via Wikipedia infobox
Chemical data
- Formula
- C16H11ClN4
- Molecular weight
- 294.74 g/mol
- IUPAC name
- 8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
- SMILES
- C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
- InChIKey
- CDCHDCWJMGXXRH-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 43.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
350 papers- Estazolam.2012
- Estazolam.2006
- Estazolam.IARC monographs on the evaluation of carcinogenic risks to humans · 1996
- Estazolam (Prosom®).1994
- Estazolam (Prosom®).1994
via PubMed
Wikidata facts
- Mass
- 294.067224
Show 6 more facts
- chemical formula
- C₁₆H₁₁ClN₄
- Commons category
- Estazolam
- World Health Organisation international non-proprietary name
- estazolam
- canonical SMILES
- C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
- defined daily dose
- 3
- MCN code
- 2933.91.23
via Wikidata · CC0
~5 min read
Article
12 sectionsContents
- Medical uses
- Side effects
- Tolerance and dependence
- Contraindications and special caution
- Pharmacology
- Pharmacokinetics
- Interactions
- EEG effects in rabbits
- Abuse
- See also
- References
- External links
Estazolam, sold under the brand name Prosom among others, is a tranquilizer medication of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Estazolam is an intermediate-acting oral benzodiazepine. It is used for short-term treatment of insomnia.
It was patented in 1968 and came into medical use in 1975.