Structure via PubChem · Public domain (PubChem)
estradiol benzoate
Sign in to saveAlso known as [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate, Eston-B, estradiol 3-benzoate, oestradiol 3-benzoate, beta-estradiol 3-benzoate, oestradiol benzoate, estra-1,3,5(10)-triene-3,17beta-diol 3-benzoate, 17beta-estradiol monobenzoate
chemical compound
In the Vinony graph
Within Vinony's link graph, estradiol benzoate is referenced by 327 other articles, and connects out to DDT, veterinary medicine and edema.
Vinony files it under Antigonadotropins, Benzoate esters and Drugs with non-standard legal status.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C25H28O3
- Molecular weight
- 376.5 g/mol
- IUPAC name
- [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC(=O)C5=CC=CC=C5
- InChIKey
- UYIFTLBWAOGQBI-BZDYCCQFSA-N
- XLogP
- 4.5
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
4,793 papers- Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx.Molecules (Basel, Switzerland) · 2022
- Methyl palmitate reversed estradiol benzoate-induced endometrial hyperplasia in female rats.Toxicology mechanisms and methods · 2021
- Intravaginal administration of estradiol benzoate capsule for estrus synchronization in goats.The Journal of reproduction and development · 2021
- Protection induced by estradiol benzoate in the MPP(+) rat model of Parkinson's disease is associated with the regulation of the inflammatory cytokine profile in the nigro striatum.Journal of neuroimmunology · 2020
- The presence of estradiol benzoate in the cervical relaxation treatment for non-surgical embryo collection does not impair embryonic morphological quality, cryosurvival, and gene expression profile.Theriogenology · 2024
via PubMed
Wikidata facts
- Mass
- 376.203845
Show 5 more facts
- chemical formula
- C₂₅H₂₈O₃
- canonical SMILES
- CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)C5=CC=CC=C5
- isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC(=O)C5=CC=CC=C5
- World Health Organisation international non-proprietary name
- estradiol benzoate
- Commons category
- Estradiol benzoate
via Wikidata · CC0