FAT4

Also known as CDHF14, CDHR11, FAT-J, FATJ, NBLA00548, VMLDS2, HKLLS2, FAT atypical cadherin 4

Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.

Gene data

FAT4

Name: FAT atypical cadherin 4
Type: protein-coding
Aliases: CDHF14, CDHR11, FAT-J, FATJ, HKLLS2, NBLA00548, VMLDS2

The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014].

via MyGene.info

Wikidata facts

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HomoloGene ID: 14377
exact match: identifiers.org/ncbigene/79633
genomic end: 126414087
genomic start: 125314918
cytogenetic location: 4q28.1

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Clinical significance
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Further reading

Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.

FAT4 is associated with the Hippo signaling pathway.