FGF7
Sign in to saveAlso known as HBGF-7, KGF, fibroblast growth factor 7
Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene.
Gene data
FGF7- Name
- fibroblast growth factor 7
- Type
- protein-coding
- Position
- 49,423,170–49,488,775 (+)
- Aliases
- HBGF-7, KGF
- Ensembl
- ENSG00000140285
- RefSeq RNA
- NM_002009.4
- RefSeq protein
- NP_002000.1
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fibroblast growth factor 7
- Symbol
- FGF7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:49,423,170-49,488,775
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FGF7 PDB 1qqk.png
Show 7 more facts
- HomoloGene ID
- 7316
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2252
- genomic end
- 49780972
- genomic start
- 49423237
- chromosome
- human chromosome 15
- cytogenetic location
- 15q21.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene.
== Function ==
Excerpted from Wikipedia’s “FGF7” article, available under the CC BY-SA 4.0 licence.