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GeneQ5425475· pop 9· linked from 94 articles

FGF21

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Also known as fibroblast growth factor 21

protein-coding gene in the species Homo sapiens

Gene data

FGF21

Name: fibroblast growth factor 21
Type: protein-coding
Position: 48,755,524–48,758,333 (+)
Ensembl: ENSG00000105550
RefSeq RNA: NM_019113.4
RefSeq protein: NP_061986.1

Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016].

Gene Ontology

Biological process

signal transduction cell-cell signaling positive regulation of cell population proliferation fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway regulation of low-density lipoprotein particle clearance neurogenesis regulation of cell migration

Molecular function

fibroblast growth factor receptor binding fibroblast growth factor receptor binding protein binding growth factor activity growth factor activity

Cellular component

extracellular region extracellular region extracellular region cytoplasm

Pathways

MAPK signaling pathway - Homo sapiens (human)Ras signaling pathway - Homo sapiens (human)Rap1 signaling pathway - Homo sapiens (human)Calcium signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Thermogenesis - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Melanoma - Homo sapiens (human)Breast cancer - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

fibroblast growth factor 21

Symbol: FGF21
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:48,755,524-48,758,333
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: FGF21.png

Show 5 more facts

HomoloGene ID: 10428
exact match: identifiers.org/ncbigene/26291
genomic end: 48758333
genomic start: 48755524
cytogenetic location: 19q13.33

Sources (6)

via Wikidata · CC0

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via Wikidata sitelinks · CC0

Categories

Aging-related proteins Anti-aging substances Genes on human chromosome 19