FGF9
Sign in to saveAlso known as FGF-9, GAF, HBFG-9, HBGF-9, SYNS3, fibroblast growth factor 9
Glia-activating factor is a protein that in humans is encoded by the FGF9 gene.
Gene data
FGF9- Name
- fibroblast growth factor 9
- Type
- protein-coding
- Position
- 21,671,067–21,704,502 (+)
- Aliases
- FGF-9, GAF, HBFG-9, HBGF-9, SYNS3
- Ensembl
- ENSG00000102678
- RefSeq RNA
- NM_002010.3, XM_011534996.3, XM_054374221.1
- RefSeq protein
- NP_002001.1, XP_011533298.1, XP_054230196.1
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fibroblast growth factor 9
- Symbol
- FGF9
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:21,671,067-21,704,502
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FGF9 PDB 1g82.png
Show 7 more facts
- HomoloGene ID
- 1523
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2254
- genomic end
- 22278637
- genomic start
- 21671073
- chromosome
- human chromosome 13
- cytogenetic location
- 13q12.11
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Function
- Sex determination
- Lung development
- Skeletal development
- Interactions
- References
- Further reading
Glia-activating factor is a protein that in humans is encoded by the FGF9 gene.
== Function ==
Excerpted from Wikipedia’s “FGF9” article, available under the CC BY-SA 4.0 licence.