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Fibroblast
Sign in to saveAlso known as fibroblasts
A fibroblast is a type of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen, produces the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
Key facts
- Cell.Name
- Fibroblast
- Cell.Latin
- fibroblastus
- Cell.Image
- NIH 3T3.jpg
- Cell.Caption
- NIH/3T3 Fibroblasts in cell culture
- Cell.Function
- Extracellular matrix and collagen creation
- Cell.Location
- Connective tissue
via Wikipedia infobox
Research
403,995 papers- A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues.Nature immunology · 2025
- Lymph node fibroblast-produced extracellular matrix shapes immune function.Trends in immunology · 2025
- Different fibroblast subtypes propel spatially defined ileal inflammation through TNFR1 signalling in murine ileitis.Nature communications · 2025
- Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.Cancer cell · 2022
- The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma.Nature communications · 2025
via PubMed
Wikidata facts
- Instance of
- cell type
- Image
- Fibroblast focus.jpg
Show 3 more facts
- Commons category
- Fibroblasts
- native label
- fibroblastus
- has characteristic
- Hayflick limit
via Wikidata · CC0
Article · Svenska
En fibroblast är en typ av bindvävscell.Fibroblasten är en avlång stationär cell med relativt lång livstid. Vid behov delar den sig. Fibroblaster producerar prokollagen som utanför cellen blir till kollagen som bygger upp så kallat extracellulär matrix. Cellen är producent av andra ECM-proteiner också, men den totala proteinproduktionen är liten, varför dess kärna har riklig förekomst av heterokromatin på grund av låg proteinsyntes. Fibroblasten härrör ur den , den kan också bildas utifrån , som finns hos vuxna individer utanför mindre blodkärl.
Abstract from DBpedia / Wikipedia · CC BY-SA