filgrastim
Sign in to saveAlso known as R-METHUG-CSF, Neupogen, Tbo-filgrastim, G-CSF, Granulocyte Colony Stimulating Factor
Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low neutrophil count. Low neutrophil counts may occur with HIV/AIDS, following chemotherapy or radiation poisoning, or be of an unknown cause. It may also be used to increase white blood cells for gathering during leukapheresis. It is given either by injection into a vein or under the skin. Filgrastim is a leukocyte growth factor.
Research
3,407 papers- Filgrastim biosimilar (EP2006): A review of 15 years' post-approval evidence.Critical reviews in oncology/hematology · 2024
- The evolution of value with filgrastim in oncology.Future oncology (London, England) · 2019
- Filgrastim induced thrombocytopenia.BMJ case reports · 2020
- Filgrastim, fibrinolysis, and neovascularization.Journal of tissue engineering and regenerative medicine · 2022
- Zarxio--a filgrastim biosimilar.The Medical letter on drugs and therapeutics · 2016
via PubMed
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Encyclopedic overview
9 sectionsContents
- Medical uses
- Adverse effects
- Interactions
- Mechanism of action
- Society and culture
- Biosimilars
- Economics
- References
- Further reading
Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low neutrophil count. Low neutrophil counts may occur with HIV/AIDS, following chemotherapy or radiation poisoning, or be of an unknown cause. It may also be used to increase white blood cells for gathering during leukapheresis. It is given either by injection into a vein or under the skin. Filgrastim is a leukocyte growth factor.
Common side effects include fever, cough, chest pain, joint pain, vomiting, and hair loss. Severe side effects include splenic rupture and allergic reactions. It is unclear if use in pregnancy is safe for the baby. Filgrastim is a recombinant form of the naturally occurring granulocyte colony-stimulating factor (G-CSF). It works by stimulating the body to increase neutrophil production.
Excerpted from Wikipedia’s “filgrastim” article, available under the CC BY-SA 4.0 licence.