MST1

Also known as D3F15S2, DNF15S2, HGFL, MSP, NF15S2, macrophage stimulating 1

Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene.

Gene data

MST1

Name: macrophage stimulating 1
Type: protein-coding
Aliases: D3F15S2, DNF15S2, HGFL, MSP, NF15S2

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010].

via MyGene.info

Gene · Ensembl

macrophage stimulating 1

Symbol: MST1
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:49,683,922-49,689,501
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein MST1 PDB 2asu.png

Show 5 more facts

HomoloGene ID: 7360
exact match: identifiers.org/ncbigene/4485
genomic end: 49726934
genomic start: 49721380
cytogenetic location: 3p21.31

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Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene.

==References==