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GeneQ17928514· pop 6· linked from 35 articles

Also known as FKBP-13, PPIase, FK506 binding protein 2, FKBP prolyl isomerase 2, FKBP13

FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.

Gene data

FKBP2
Name
FKBP prolyl isomerase 2
Type
protein-coding
Position
64,241,003–64,244,583 (+)
Aliases
FKBP-13, FKBP13, PPIase
RefSeq RNA
NM_001135208.2, NM_001370360.1, NM_001370362.1, NM_001370363.1, NM_001370365.1
RefSeq protein
NP_001128680.1, NP_001357289.1, NP_001357291.1, NP_001357292.1, NP_001357294.1

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008].

via MyGene.info

Gene · Ensembl

FKBP prolyl isomerase 2

Symbol
FKBP2
Biotype
Protein coding
Organism
Homo sapiens
Location
11:64,241,003-64,244,583
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein FKBP2 PDB 2pbc.png
Show 7 more facts
HomoloGene ID
40604
found in taxon
Homo sapiens
genomic start
64008475
genomic end
64244134
cytogenetic location
11q13.1
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.

== Function ==

Excerpted from Wikipedia’s “FKBP2” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0