FKBP2
Sign in to saveAlso known as FKBP-13, PPIase, FK506 binding protein 2, FKBP prolyl isomerase 2, FKBP13
FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.
Gene data
FKBP2- Name
- FKBP prolyl isomerase 2
- Type
- protein-coding
- Aliases
- FKBP-13, FKBP13, PPIase
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008].
via MyGene.info
Wikidata facts
- Image
- Protein FKBP2 PDB 2pbc.png
Show 5 more facts
- HomoloGene ID
- 40604
- exact match
- identifiers.org/ncbigene/2286
- genomic start
- 64008475
- genomic end
- 64244134
- cytogenetic location
- 11q13.1
Sources (4)
via Wikidata · CC0
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Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.
== Function ==