Flavivirus
Sign in to saveOrthoflavivirus (Flavivirus prior to 2023; common name orthoflavivirus, orthoflaviviral or orthoflaviviruses) is a genus of positive-strand RNA viruses in the family Flaviviridae. The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV). While dual-host flaviviruses can infect vertebrates as well as arthropods, insect-specific flaviviruse
Species
GENUS
- KingdomViruses
- PhylumKitrinoviricota
- ClassFlasuviricetes
- OrderAmarillovirales
- FamilyFlaviviridae
via GBIF
Research
38,269 papers- Pathogenesis and virulence of flavivirus infections.Virulence · 2021
- TRIMming down Flavivirus Infections.Viruses · 2024
- Flavivirus Persistence in Wildlife Populations.Viruses · 2021
- Flavivirus NS4B protein: Structure, function, and antiviral discovery.Antiviral research · 2022
- Flavivirus infection-A review of immunopathogenesis, immunological response, and immunodiagnosis.Virus research · 2019
via PubMed
~22 min read
Encyclopedic overview
22 sectionsContents
- History and name
- Structure
- Genome
- Life cycle
- RNA secondary structure elements
- 5'UTR
- 3'UTR
- Conserved hairpin cHP
- The role of RNA secondary structures in sfRNA production
- Evolution
- Taxonomy
- Species
- Sorted by vector
- Tick-borne viruses
- Mosquito-borne viruses
- Viruses with no known arthropod vector
- Non vertebrate viruses
- Viruses known only from sequencing
- Vaccines
- References
- Further reading
- External links
Orthoflavivirus (Flavivirus prior to 2023; common name orthoflavivirus, orthoflaviviral or orthoflaviviruses) is a genus of positive-strand RNA viruses in the family Flaviviridae. The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV). While dual-host flaviviruses can infect vertebrates as well as arthropods, insect-specific flaviviruses are restricted to their competent arthropods. The means by which flaviviruses establish persistent infection in their competent vectors and cause disease in humans depends upon several virus-host interactions, including the intricate interplay between flavivirus-encoded immune antagonists and the host antiviral innate immune effector molecules.
Orthoflaviviruses are named for the yellow fever virus; the word flavus means 'yellow' in Latin, and yellow fever in turn is named from its propensity to cause yellow jaundice in victims.
Excerpted from Wikipedia’s “Flavivirus” article, available under the CC BY-SA 4.0 licence.