Flavivirus
Sign in to saveOrthoflavivirus (Flavivirus prior to 2023; common name orthoflavivirus, orthoflaviviral or orthoflaviviruses) is a genus of positive-strand RNA viruses in the family Flaviviridae. The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV). While dual-host flaviviruses can infect vertebrates as well as arthropods, insect-specific flaviviruse
Species
GENUS
- KingdomViruses
- PhylumKitrinoviricota
- ClassFlasuviricetes
- OrderAmarillovirales
- FamilyFlaviviridae
Habitatmarine
via GBIF
Research
38,269 papers- Pathogenesis and virulence of flavivirus infections.Virulence · 2021
- TRIMming down Flavivirus Infections.Viruses · 2024
- Flavivirus Persistence in Wildlife Populations.Viruses · 2021
- Flavivirus NS4B protein: Structure, function, and antiviral discovery.Antiviral research · 2022
- Flavivirus infection-A review of immunopathogenesis, immunological response, and immunodiagnosis.Virus research · 2019
via PubMed
Wikidata facts
- Instance of
- taxon
- Parent taxon
- Flaviviridae
- Named after
- yellow fever
- Image
- YellowFeverVirus.jpg
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via Wikidata · CC0
Article
22 sectionsContents
- History and name
- Structure
- Genome
- Life cycle
- RNA secondary structure elements
- 5'UTR
- 3'UTR
- Conserved hairpin cHP
- The role of RNA secondary structures in sfRNA production
- Evolution
- Taxonomy
- Species
- Sorted by vector
- Tick-borne viruses
- Mosquito-borne viruses
- Viruses with no known arthropod vector
- Non vertebrate viruses
- Viruses known only from sequencing
- Vaccines
- References
- Further reading
- External links
Orthoflavivirus (Flavivirus prior to 2023; common name orthoflavivirus, orthoflaviviral or orthoflaviviruses) is a genus of positive-strand RNA viruses in the family Flaviviridae. The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV). While dual-host flaviviruses can infect vertebrates as well as arthropods, insect-specific flaviviruses are restricted to their competent arthropods. The means by which flaviviruses establish persistent infection in their competent vectors and cause disease in humans depends upon several virus-host interactions, including the intricate interplay between flavivirus-encoded immune antagonists and the host antiviral innate immune effector molecules.
Orthoflaviviruses are named for the yellow fever virus; the word flavus means 'yellow' in Latin, and yellow fever in turn is named from its propensity to cause yellow jaundice in victims.