Structure via PubChem · Public domain (PubChem)
favipiravir
Sign in to saveAlso known as T-705, favilavir, 5-fluoro-2-hydroxypyrazine-3-carboxamide
Favipiravir, sold under the brand name Avigan among others, is an antiviral medication used to treat influenza in Japan. It is also being studied to treat a number of other viral infections, including SARS-CoV-2. Like the experimental antiviral drugs T-1105 and T-1106, it is a pyrazinecarboxamide derivative.
Key facts
- Drug.image
- Favipiravir.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Favipiravir-from-xtal-Mercury-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- , Avifavir, Areplivir, others
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- J05
- Drug.ATC_suffix
- AX27
- Drug.legal_status
- Rx-only
- Drug.CAS_number
- 259793-96-9
- Drug.PubChem
- 492405
- Drug.DrugBank
- DB12466
- Drug.ChemSpiderID
- 431002
- Drug.UNII
- EW5GL2X7E0
- Drug.KEGG
- D09537
- Drug.ChEBI
- 134722
- Drug.ChEMBL
- 221722
- Drug.synonyms
- T-705, favipira, favilavir
via Wikipedia infobox
Chemical data
- Formula
- C5H4FN3O2
- Molecular weight
- 157.1 g/mol
- IUPAC name
- 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
- SMILES
- C1=C(N=C(C(=O)N1)C(=O)N)F
- InChIKey
- ZCGNOVWYSGBHAU-UHFFFAOYSA-N
- XLogP
- -0.6
- Polar surface area
- 84.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 157.029
- Has use
- medication
Show 8 more facts
- chemical formula
- C₅H₄FN₃O₂
- canonical SMILES
- C1=C(N=C(C(=O)N1)C(=O)N)F
- route of administration
- oral administration
- subject has role
- antiviral drug
- World Health Organisation international non-proprietary name
- favipiravir
- pKa
- 5.1
- melting point
- 187
- Commons category
- Favipiravir
Sources (7)
via Wikidata · CC0
~9 min read
Encyclopedic overview
16 sectionsContents
- Medical use
- Side effects
- Mechanism of action
- Synthesis
- Society and culture
- Legal status
- Brand names
- Use in Russia
- Research
- COVID-19
- Ebola
- Nipah
- Other
- Tautomerism
- References
- External links
Favipiravir, sold under the brand name Avigan among others, is an antiviral medication used to treat influenza in Japan. It is also being studied to treat a number of other viral infections, including SARS-CoV-2. Like the experimental antiviral drugs T-1105 and T-1106, it is a pyrazinecarboxamide derivative.
It is being developed and manufactured by Toyama Chemical (a subsidiary of Fujifilm) and was approved for medical use in Japan in 2014. In 2016, Fujifilm licensed it to Zhejiang Hisun Pharmaceutical Co. It became a generic drug in 2019.
Excerpted from Wikipedia’s “favipiravir” article, available under the CC BY-SA 4.0 licence.