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EntityQ2393323· pop 15· linked from 485 articles

chlorcyclizine

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Also known as Chlorcyclizin, Chlorcyclizinum, Clorciclizina

Chlorcyclizine (Di-Paralene, Mantadil, Pruresidine, Trihistan) is a first-generation antihistamine of the diphenylmethylpiperazine group marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine has some anticholinergic, antiserotonergic, and local anesthetic properties. It has been studied as a potential treatment for various flaviviruses like hepatitis C and Zika virus.

Wikidata facts

Mass
300.139
Has use
medication
Show 6 more facts
Commons category
Chlorcyclizine
chemical formula
C₁₈H₂₁ClN₂
medical condition treated
allergic rhinitis
canonical SMILES
CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
defined daily dose
0.1
subject has role
H1 antagonist
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Encyclopedic overview

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Chlorcyclizine (Di-Paralene, Mantadil, Pruresidine, Trihistan) is a first-generation antihistamine of the diphenylmethylpiperazine group marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine has some anticholinergic, antiserotonergic, and local anesthetic properties. It has been studied as a potential treatment for various flaviviruses like hepatitis C and Zika virus.

== See also == Cyclizine Homochlorcyclizine Meclizine

Excerpted from Wikipedia’s “chlorcyclizine” article, available under the CC BY-SA 4.0 licence.