FMO2
Sign in to saveAlso known as FMO1B1, flavin containing monooxygenase 2, flavin containing dimethylaniline monoxygenase 2
Gen der Spezies Homo sapiens
Gene data
FMO2- Name
- flavin containing dimethylaniline monoxygenase 2
- Type
- protein-coding
- Position
- 171,185,249–171,212,686 (+)
- Aliases
- FMO1B1
- Ensembl
- ENSG00000094963
- RefSeq RNA
- NM_001301347.2, NM_001365900.2, NM_001426376.1, NM_001426378.1, NM_001426379.1
- RefSeq protein
- NP_001288276.1, NP_001352829.1, NP_001413305.1, NP_001413307.1, NP_001413308.1
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
flavin containing dimethylaniline monoxygenase 2
- Symbol
- FMO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:171,185,249-171,212,686
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 86882
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2327
- chromosome
- human chromosome 1
- genomic start
- 171185249
- genomic end
- 171212686
- cytogenetic location
- 1q24.3
Sources (4)
via Wikidata · CC0