FOXG1
Sign in to saveAlso known as BF1, BF2, FHKL3, FKH2, FKHL1, FKHL2, FKHL3, FKHL4
Forkhead box protein G1 is a protein that in humans is encoded by the FOXG1 gene.
Gene data
FOXG1- Name
- forkhead box G1
- Type
- protein-coding
- Position
- 28,764,329–28,770,277 (+)
- Aliases
- BF1, BF2, FHKL3, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B
- Ensembl
- ENSG00000176165
- RefSeq RNA
- NM_005249.5
- RefSeq protein
- NP_005240.3
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
forkhead box G1
- Symbol
- FOXG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:28,764,329-28,770,277
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 3843
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2290
- genomic end
- 29238870
- genomic start
- 28766787
- chromosome
- human chromosome 14
- cytogenetic location
- 14q12
- genetic association
- Rett syndrome
- expressed in
- postcentral gyrus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
7 sectionsContents
- Function
- Associated disorders
- Interactions
- See also
- References
- Further reading
- External links
Forkhead box protein G1 is a protein that in humans is encoded by the FOXG1 gene.
== Function ==
Excerpted from Wikipedia’s “FOXG1” article, available under the CC BY-SA 4.0 licence.