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ganciclovir

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EntityQ417640· pop 26· linked from 125 articles

ganciclovir

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Also known as Vitrasert, GA2, 2-amino-9-((1,3-Dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one, Ganciclovirum, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, 2-amino-9-((1,3-Dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol, Gancyclovir

Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.

In the Vinony graph

Vinony's link graph records 125 inbound references to ganciclovir, and connects out to antiviral drug, neomycin and nucleoside analogue.

It is catalogued under topics including Anti-herpes virus drugs, Cell culture reagents and Diols.

Vinony links it to 25 Wikipedia language editions.

Chemical data

Formula
C9H13N5O4
Molecular weight
255.23 g/mol
IUPAC name
2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one
SMILES
C1=NC2=C(N1COC(CO)CO)N=C(NC2=O)N
InChIKey
IRSCQMHQWWYFCW-UHFFFAOYSA-N
XLogP
-2.5
Polar surface area
135 Ų
H-bond donors
4
H-bond acceptors
6
Formal charge
0

via PubChem

Wikidata facts

Mass
255.097
Show 4 more facts
Commons category
Ganciclovir
chemical formula
C₉H₁₃N₅O₄
World Health Organisation international non-proprietary name
ganciclovir
canonical SMILES
C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
Sources (8)

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Encyclopedic overview

10 sections
Contents
  • Medical use
  • Veterinary use
  • Adverse effects
  • Toxicity
  • Mechanism of action
  • Pharmacokinetics
  • Administration
  • See also
  • References
  • Further reading

Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.

Ganciclovir was patented in 1980 and approved for medical use in 1988.

Excerpted from Wikipedia’s “ganciclovir” article, available under the CC BY-SA 4.0 licence.

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