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gastroparesis

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Also known as gastric atonia (disorder), gastric atonia, delayed gastric emptying, gastroparalysis, gastroparesis syndrome (disorder) [Ambiguous], gastroparesis syndrome

Gastroparesis (gastro- from Ancient Greek  – gaster, "stomach"; and -paresis, πάρεσις – "partial paralysis") is a medical disorder of ineffective neuromuscular contractions (peristalsis) of the stomach, resulting in food and liquid remaining in the stomach for a prolonged period. Stomach contents thus exit more slowly into the duodenum of the digestive tract, a medical sign called delayed gastric emptying. The opposite of this, where stomach contents exit quickly into the duodenum, is called dumping syndrome.

Key facts

Medical condition (new).name
Gastroparesis
Medical condition (new).pronounce
(/,ɡæstroʊ,pəˈriːsɪs/)
Medical condition (new).image
GastroparesisXray.jpg
Medical condition (new).caption
Simple abdominal X-ray shows gastric distension with a large amount of material in the stomach, suggesting severe gastric hypomotility
Medical condition (new).field
Gastroenterology
Medical condition (new).symptoms
Nausea, vomiting, abdominal pain, feeling full after consuming very little ("early satiety")
Medical condition (new).complications
Malnutrition, fatigue, weight loss, vitamin deficiencies, intestinal obstruction due to bezoars, small intestinal bacterial overgrowth, Anorexia
Medical condition (new).causes
Connective tissue disorders, damage to the vagus nerve, chemotherapy-induced neuropathy, autonomic neuropathy
Medical condition (new).risks
Diabetes, abdominal or esophageal surgery, infection, certain medications that slow the rate of stomach emptying, scleroderma, nervous system diseases, hypothyroidism,
Medical condition (new).diagnosis
Barium swallow X-ray, barium beefsteak meal, radioisotope gastric-emptying scan (GES), wireless motility capsule (WMC), serial X-ray after ingesting radiopaque markers (ROM), gastric manometry, esophagogastroduodenoscopy (EGD), stable isotope breath test
Medical condition (new).differential
Peptic ulcer disease, gastric outlet obstruction, functional dyspepsia
Medical condition (new).treatment
Dietary modifications, medications to stimulate gastric emptying, medications to reduce vomiting gastric electrical stimulation

via Wikipedia infobox

Research

4,928 papers

via PubMed

Wikidata facts

Subclass of
disease
Image
GastroparesisXray.jpg
Show 7 more facts
NCI Thesaurus ID
C80512
health specialty
gastroenterology
symptoms and signs
fecal incontinence
ICD-9-CM
536.3
Commons category
Gastroparesis
on focus list of Wikimedia project
WikiProject Medicine
Sources (3)

via Wikidata · CC0

~30 min read

Encyclopedic overview

31 sections
Contents
  • Signs and symptoms
  • Complications
  • Causes
  • Idiopathic
  • Chronic conditions
  • Other causes
  • Physiology and mechanism
  • Diagnosis
  • Differential diagnosis
  • Testing overview
  • Gastric emptying scintigraphy
  • Stable isotope breath tests with carbon-13
  • Wireless motility capsule
  • Antroduodenal manometry
  • Other imaging tests
  • Treatment
  • Diet
  • Pharmacotherapy
  • Dopamine antagonists
  • Other prokinetics
  • Other neuromodulators and antiemetics
  • Other agents
  • Deprescribing
  • Drug development
  • Other therapeutic interventions
  • Prognosis
  • Prevalence
  • See also
  • References
  • Further reading
  • External links

Gastroparesis (gastro- from Ancient Greek  – gaster, "stomach"; and -paresis, πάρεσις – "partial paralysis") is a medical disorder of ineffective neuromuscular contractions (peristalsis) of the stomach, resulting in food and liquid remaining in the stomach for a prolonged period. Stomach contents thus exit more slowly into the duodenum of the digestive tract, a medical sign called delayed gastric emptying. The opposite of this, where stomach contents exit quickly into the duodenum, is called dumping syndrome.

Symptoms include nausea, vomiting, abdominal pain, feeling full soon after beginning to eat (early satiety), abdominal bloating, and heartburn. Many or most cases are idiopathic. The most commonly known cause is autonomic neuropathy of the vagus nerve, which innervates the stomach. Uncontrolled diabetes mellitus is a frequent cause of this nerve damage, but trauma to the vagus nerve is also possible. Some cases may be considered post-infectious.

Excerpted from Wikipedia’s “gastroparesis” article, available under the CC BY-SA 4.0 licence.