جنتامایسین

Also known as gentamicin sulfate, gentamycin, gentamicins

یک داروی آنتی‌بیوتیک

OverviewAI-generated

Gentamicin is a chemical compound with the formula C₂₁H₄₃N₅O₇. It has a molecular mass of 477.316249 and a weight of 477.6. The substance carries a charge of 0 and possesses an xlogp value of -4.1. Its topological polar surface area is 200, with 8 hydrogen bond donors and 12 hydrogen bond acceptors.

The defined daily dose for gentamicin is 0.24. The compound is associated with a PubMed query count of 38434. It is referenced by 378 other encyclopedia articles.

Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Chemical data

Formula: C21H43N5O7
Molecular weight: 477.6 g/mol
IUPAC name: 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC
InChIKey: CEAZRRDELHUEMR-UHFFFAOYSA-N
XLogP: -4.1
Polar surface area: 200 Å²
H-bond donors: 8
H-bond acceptors: 12
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Research

38,434 papers

Gentamicin vestibulotoxicity.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 1994
Gentamicin in 1978.Annals of internal medicine · 1978
Gentamicin-induced anaphylaxis.Irish journal of medical science · 2007
Use of Gentamicin as Empiric Coverage for Ventilator-Associated Pneumonia: The "Con" Perspective.Surgical infections · 2016
Microbial biosynthesis and applications of gentamicin: a critical appraisal.Critical reviews in biotechnology · 2008

via PubMed

Wikidata facts

Instance of: extract
Has part: sulfate
Mass: 477.316249
Image: Gentamicin for injection.jpg
Has use: essential medicine

Show 9 more facts

found in taxon: Micromonospora
medical condition treated: infective endocarditis
legal status (medicine): boxed warning
Commons category: Gentamicin
chemical formula: C₂₁H₄₃N₅O₇
canonical SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC
defined daily dose: 0.24
NCI Thesaurus ID: C519
subject has role: antibiotic