glycocyamine
Sign in to saveAlso known as Betacyamine, Guanidoacetic acid, Amidinoglycine, N-(aminoiminomethyl)glycine, Guanyl glycine, N-amidinoglycine, Guanidineacetic acid
Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine by guanylation (transfer of a guanidine group from arginine). In vertebrate organism it is then transformed into creatine by methylation.
Research
484 papersvia PubMed
Wikidata facts
- Subclass of
- ion
- Mass
- 117.054
Show 6 more facts
- chemical formula
- C₃H₇N₃O₂
- canonical SMILES
- C(C(=O)O)N=C(N)N
- found in taxon
- Malus domestica
- subject has role
- primary metabolite
- isomeric SMILES
- O=C(O)CNC(=N)N
- Commons category
- Glycocyamine
via Wikidata · CC0
~4 min read
Encyclopedic overview
9 sectionsContents
- Production
- Biochemical synthesis
- Chemical synthesis
- Properties
- Uses
- As a supplement
- As a feed additive
- References
- See also
Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine by guanylation (transfer of a guanidine group from arginine). In vertebrate organism it is then transformed into creatine by methylation.
Glycocyamine is used as a supplement and as a feed additive in poultry farming. However, the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups. This causes homocysteine levels to rise, which has been shown to produce cardiovascular and skeletal problems. Glycocyamine plays a role in the metabolism of the amino acids serine, threonine, and proline.
Excerpted from Wikipedia’s “glycocyamine” article, available under the CC BY-SA 4.0 licence.