sarcosine
Sign in to saveSarcosine, also known as '''N-methylglycine, or monomethylglycine', is a non-proteinogenic amino acid with the formula CH3N(H)CH2CO2H. It is the N''-methyl derivative of glycine, with a secondary amine in place of the primary amine, and occurs naturally in muscles and other body tissues as an intermediate in the metabolism of choline to glycine. It was first isolated and named by the German chemist Justus von Liebig in 1847.
Article
14 sectionsContents
- Chemistry
- Industrial synthesis
- Surfactants
- Biochemistry
- Distribution
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Research
- Schizophrenia
- Prostate cancer
- History
- See also
- References
Sarcosine, also known as '''N-methylglycine, or monomethylglycine', is a non-proteinogenic amino acid with the formula CH3N(H)CH2CO2H. It is the N-methyl derivative of glycine, with a secondary amine in place of the primary amine, and occurs naturally in muscles and other body tissues as an intermediate in the metabolism of choline to glycine. It was first isolated and named by the German chemist Justus von Liebig in 1847.
Sarcosine is ubiquitous in biological materials. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. It is also a reagent in organic synthesis. It has a mildly sweet taste.