Gene data
GNB1- Name
- G protein subunit beta 1
- Type
- protein-coding
- Position
- 1,785,285–1,892,292 (−)
- Aliases
- HG2A, MDS, MRD42
- Ensembl
- ENSG00000078369
- RefSeq RNA
- NM_001282538.2, NM_001282539.2, NM_002074.5, XM_017001059.3, XM_017001060.3
- RefSeq protein
- NP_001269467.1, NP_001269468.1, NP_002065.1, XP_016856548.1, XP_016856549.1
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
signal transductionsignal transductionG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating dopamine receptor signaling pathwayG protein-coupled acetylcholine receptor signaling pathwayRas protein signal transductioncellular response to prostaglandin E stimulus
Molecular function
Pathways
Ras signaling pathway - Homo sapiens (human)Chemokine signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Apelin signaling pathway - Homo sapiens (human)Circadian entrainment - Homo sapiens (human)Retrograde endocannabinoid signaling - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Cholinergic synapse - Homo sapiens (human)Serotonergic synapse - Homo sapiens (human)GABAergic synapse - Homo sapiens (human)
via MyGene.info
Wikidata facts
- Image
- Protein GNB1 PDB 1a0r.png
Show 5 more facts
- HomoloGene ID
- 55532
- exact match
- identifiers.org/ncbigene/2782
- genomic end
- 1822495
- genomic start
- 1716729
- cytogenetic location
- 1p36.33
via Wikidata · CC0
~1 min read
Article
7 sectionsContents
- Function
- Interactive pathway map
- Interactions
- Mutations
- References
- Further reading
- External links
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Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene.
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via Wikidata sitelinks · CC0
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