GNGT1
Sign in to saveAlso known as GNG1, G protein subunit gamma transducin 1, HG3G1
Guanine nucleotide-binding protein G(T) subunit gamma-T1 is a protein that in humans is encoded by the GNGT1 gene. Either GNGT1 or GNGT2 is the gamma subunit (Gγ) of the Gβγ part of transducin (written G(T) or Gt), a heterotrimeric G-protein naturally expressed in vertebrate retina rod and cone cells. GNGT1 only occurs in rod cells, and GNGT2 only occurs in cone cells, with a different alpha (Gα) subunit.
In the Vinony graph
Within Vinony's link graph, GNGT1 is referenced by 89 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Its subject is documented across 7 Wikipedia language editions.
Gene data
GNGT1- Name
- G protein subunit gamma transducin 1
- Type
- protein-coding
- Position
- 93,591,329–93,911,265 (+)
- Aliases
- GNG1, HG3G1
- Ensembl
- ENSG00000127928
- RefSeq RNA
- NM_001329426.2, NM_021955.5
- RefSeq protein
- NP_001316355.1, NP_068774.1
This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit gamma transducin 1
- Symbol
- GNGT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:93,591,329-93,911,265
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GNGT1 PDB 1a0r.png
Show 8 more facts
- HomoloGene ID
- 7738
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2792
- genomic end
- 93540577
- genomic start
- 93220885
- chromosome
- human chromosome 7
- cytogenetic location
- 7q21.3
- expressed in
- thymus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Guanine nucleotide-binding protein G(T) subunit gamma-T1 is a protein that in humans is encoded by the GNGT1 gene. Either GNGT1 or GNGT2 is the gamma subunit (Gγ) of the Gβγ part of transducin (written G(T) or Gt), a heterotrimeric G-protein naturally expressed in vertebrate retina rod and cone cells. GNGT1 only occurs in rod cells, and GNGT2 only occurs in cone cells, with a different alpha (Gα) subunit.
==References==
Excerpted from Wikipedia’s “GNGT1” article, available under the CC BY-SA 4.0 licence.