goserelin
Sign in to saveGoserelin, sold under the brand name Zoladex among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast cancer and prostate cancer. It is an injectable gonadotropin releasing hormone agonist (GnRH agonist).
Research
2,150 papers- Goserelin ('Zoladex')--offering patients more choice in early breast cancer.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2004
- Clinical pharmacokinetics of goserelin.Clinical pharmacokinetics · 2000
- Goserelin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in benign gynaecological disorders.Drugs · 1996
- Goserelin: a review of its use in the treatment of early breast cancer in premenopausal and perimenopausal women.Drugs · 2005
- Goserelin. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in prostate cancer.Drugs & aging · 1995
via PubMed
Article
7 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Chemistry
- Society and culture
- Names
- References
Goserelin, sold under the brand name Zoladex among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast cancer and prostate cancer. It is an injectable gonadotropin releasing hormone agonist (GnRH agonist).
Structurally, it is a decapeptide. It is the natural GnRH decapeptide with two substitutions to inhibit rapid degradation.
Gallery (2)
Connections
Categories
DecapeptidesDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs developed by AstraZenecaDrugs with non-standard legal statusECHA InfoCard ID from WikidataFeminizing hormone therapyGonadotropin-releasing hormone agonistsWorld Health Organization essential medicines