zolmitriptan

Also known as (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-{[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one, 4-{[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one

Zolmitriptan, sold under the brand name Zomig among others, is a serotonergic medication which is used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is taken by mouth as a swallowed or disintegrating tablet or as a nasal spray.

Chemical data

Formula: C16H21N3O2
Molecular weight: 287.36 g/mol
IUPAC name: (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
InChIKey: ULSDMUVEXKOYBU-ZDUSSCGKSA-N
XLogP: 2.2
Polar surface area: 57.4 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

730 papers

~12 min read

Article

28 sections

Contents

Medical uses
Migraine
Off-label uses
Available forms
Contraindications
Side effects
Overdose
Interactions
Pharmacology
Pharmacodynamics
Pharmacokinetics
Absorption
Distribution
Metabolism
Elimination
Chemistry
History
Society and culture
Brand names
Economics
Legal status
Research
Obsessive–compulsive disorder
Social deficits and aggression
See also
References
Further reading
External links

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