Structure via PubChem · Public domain (PubChem)
atenolol
Sign in to saveAlso known as Myocord®, Normiten®, Tenormin®, 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide, 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, Duratenol, Blokium
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. Although used to treat high blood pressure, it does not seem to improve mortality in those with the condition. Other uses include the prevention of migraines and treatment of certain irregular heart beats. It is taken orally (by mouth) or by intravenous injection (injection into a vein). It can also be used with other blood pressure medications.
Key facts
- Drug.image
- Atenolol structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- Atenolol_3d_structure.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Tenormin, others
- Drug.MedlinePlus
- a684031
- Drug.DailyMedID
- Atenolol
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- Oral, intravenous
- Drug.class
- Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist; Sympatholytic agent; Antihypertensive agent; Anxiolytic
- Drug.ATC_prefix
- C07
- Drug.ATC_suffix
- AB03
- Drug.legal_AU
- S4
- Drug.legal_US
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.bioavailability
- 50–60%
via Wikipedia infobox
Chemical data
- Formula
- C14H22N2O3
- Molecular weight
- 266.34 g/mol
- IUPAC name
- 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
- SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O
- InChIKey
- METKIMKYRPQLGS-UHFFFAOYSA-N
- XLogP
- 0.2
- Polar surface area
- 84.6 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
8,935 papers- Atenolol in hypertension: is it a wise choice?Lancet (London, England) · 2004
- Atenolol. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders.Drugs · 1991
- Clinical pharmacokinetics of atenolol--a review.European journal of drug metabolism and pharmacokinetics · 1982
- Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension.Drugs · 1979
- A synthesis on the sub-lethal toxicity of atenolol, a beta-blocker, in teleost fish.Environmental toxicology and pharmacology · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 266.163043
- Has use
- medication
Show 9 more facts
- chemical formula
- C₁₄H₂₂N₂O₃
- medical condition treated
- ventricular fibrillation
- canonical SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O
- World Health Organisation international non-proprietary name
- atenolol
- Commons category
- Atenolol
- significant drug interaction
- disopyramide
- physically interacts with
- adrenoceptor beta 2
- legal status (medicine)
- boxed warning
- defined daily dose
- 75
Sources (8)
via Wikidata · CC0
~14 min read
Encyclopedic overview
17 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- History
- Society and culture
- Changing medical practices
- References
{{Infobox drug | image = Atenolol structure.svg | image_class = skin-invert-image | width = 250 | alt = | image2 = Atenolol_3d_structure.png | image_class2 = bg-transparent | width2 = 250 | alt2 =
| tradename = Tenormin, others | Drugs.com = | MedlinePlus = a684031 | DailyMedID = Atenolol | pregnancy_AU = C | routes_of_administration = Oral, intravenous | class = Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist; Sympatholytic agent; Antihypertensive agent; Anxiolytic | ATC_prefix = C07 | ATC_suffix = AB03
Excerpted from Wikipedia’s “atenolol” article, available under the CC BY-SA 4.0 licence.