GPA33
Sign in to saveAlso known as A33, glycoprotein A33
Cell surface A33 antigen is a protein that in humans is encoded by the GPA33 gene.
Gene data
GPA33- Name
- glycoprotein A33
- Type
- protein-coding
- Position
- 167,048,289–167,166,479 (−)
- Aliases
- A33
- Ensembl
- ENSG00000143167
- RefSeq RNA
- NM_005814.3, XM_017000005.2, XM_047424480.1, XM_054333756.1, XM_054333757.1
- RefSeq protein
- NP_005805.1, XP_016855494.1, XP_047280436.1, XP_054189731.1, XP_054189732.1
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
glycoprotein A33
- Symbol
- GPA33
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:167,048,289-167,166,479
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4245
- exact match
- identifiers.org/ncbigene/10223
- genomic end
- 167059868
- genomic start
- 167022073
- cytogenetic location
- 1q24.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Cell surface A33 antigen is a protein that in humans is encoded by the GPA33 gene.
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.