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GeneQ18044733· pop 6· linked from 70 articles

Also known as BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3, cell adhesion molecule 3, CMT2FF

Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene.

Gene data

CADM3
Name
cell adhesion molecule 3
Type
protein-coding
Aliases
BIgR, CMT2FF, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3

The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016].

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Wikidata facts

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HomoloGene ID
10919
genomic start
159141399
genomic end
159173103
cytogenetic location
1q23.2
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Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene.

IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005).

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