Structure via PubChem · Public domain (PubChem)
guaiacol
Sign in to saveAlso known as 2-Hydroxyanisole, 1-Hydroxy-2-methoxybenzene, 2-methoxyphenol, Guasol, Pyroguaiac acid, Methoxyphenol, Guaiacol (liquid) extra pure
Guaiacol () is an organic compound with the formula C6H4(OH)(OCH3). It is a phenolic compound containing a methoxy functional group. Guaiacol appears as a viscous colorless oil, although aged or impure samples are often yellowish. It occurs widely in nature and is a common product of the pyrolysis of wood.
Chemical data
- Formula
- C7H8O2
- Molecular weight
- 124.14 g/mol
- IUPAC name
- 2-methoxyphenol
- SMILES
- COC1=CC=CC=C1O
- InChIKey
- LHGVFZTZFXWLCP-UHFFFAOYSA-N
- XLogP
- 1.3
- Polar surface area
- 29.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
5,197 papers- Guaiacol augments quorum quenching potential of ciprofloxacin against Pseudomonas aeruginosa.Journal of applied microbiology · 2022
- Synthetic Guaiacol Derivatives as Promising Myeloperoxidase Inhibitors Targeting Atherosclerotic Cardiovascular Disease.ChemMedChem · 2020
- Guaiacol as a natural melanin biosynthesis inhibitor to control northern corn leaf blight.Pest management science · 2022
- Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C-Src and inhibiting NF-κB, MAPK and AKT pathways.Journal of cellular and molecular medicine · 2020
- Guaiacol oxidation activity of herbivorous land crabs, Chiromantes haematocheir and Chiromantes dehaani.Journal of bioscience and bioengineering · 2019
via PubMed
Wikidata facts
- Mass
- 124.052
Show 5 more facts
- Commons gallery
- Guaiacol
- Commons category
- Guaiacol
- chemical formula
- C₇H₈O₂
- canonical SMILES
- COC1=CC=CC=C1O
- melting point
- 30.0
via Wikidata · CC0
~4 min read
Article
10 sectionsContents
- Occurrence
- Preparation
- Laboratory methods
- Uses and chemical reactions
- Syringyl/guaiacyl ratio
- Chemical intermediate
- Medicinal and food
- Safety
- See also
- References
Guaiacol () is an organic compound with the formula C6H4(OH)(OCH3). It is a phenolic compound containing a methoxy functional group. Guaiacol appears as a viscous colorless oil, although aged or impure samples are often yellowish. It occurs widely in nature and is a common product of the pyrolysis of wood.
==Occurrence== Guaiacol is usually derived from guaiacum or wood creosote.