Structure via PubChem · Public domain (PubChem)
haloxazolam
Sign in to saveHaloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.
Chemical data
- Formula
- C17H14BrFN2O2
- Molecular weight
- 377.2 g/mol
- IUPAC name
- 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
- SMILES
- C1COC2(N1CC(=O)NC3=C2C=C(C=C3)Br)C4=CC=CC=C4F
- InChIKey
- XDKCGKQHVBOOHC-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 376.022
Show 3 more facts
- chemical formula
- C₁₇H₁₄BrFN₂O₂
- canonical SMILES
- C1COC2(N1CC(=O)NC3=C2C=C(C=C3)Br)C4=CC=CC=C4F
- Commons category
- Haloxazolam
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Haloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.
== See also == Benzodiazepine
Excerpted from Wikipedia’s “haloxazolam” article, available under the CC BY-SA 4.0 licence.